Epothilone B | Patupilone | EPO 906 | CAS 152044-54-7

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	￥486.00	Visible after login	- +
10 mg	3-5days	￥836.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

5 mg

3-5days

￥486.00

Visible after login

- +

10 mg

3-5days

￥836.00

Visible after login

- +

Product Overview

Product Name	Epothilone B \| Patupilone \| EPO 906
CAS	152044-54-7
Formula	C27H41NO6S
MW	507.68
Appearance	White to off-white powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Epothilone B is a microtubule stabilizer with a K_i of 0.71μM. It acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation.

Related literature

Synthesis and biological activity of novel epothilone aziridines.

PMID: 11506611 DOI: 10.1021/ol016273w

Epothilone B inhibits migration of glioblastoma cells by inducing microtubule catastrophes and affecting EB1 accumulation at microtubule plus ends.

PMID: 22634050 DOI: 10.1016/j.bcp.2012.05.010

The microtubule stabilizer patupilone (epothilone B) is a potent radiosensitizer in medulloblastoma cells.

PMID: 21743064 PMCID: PMC3158010 DOI: 10.1093/neuonc/nor069

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History

CL2416

Epothilone B | Patupilone | EPO 906

152044-54-7 98+%

埃博霉素B | 帕土匹龙

Chemical safety data sheet(MSDS)