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Home > Category > Signaling Pathways > TGF-beta/Smad > TGF-beta/Smad inhibitor > A 83-01 | A-83-01

A 83-01 | A-83-01

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Catalog No：CL2598 CAS No.：909910-43-6 MDLNo： Formula：C25H19N5S MW：421.52
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Product Overview
Product Name A 83-01 | A-83-01
CAS909910-43-6
FormulaC25H19N5S
MW421.52
AppearanceOff-white to light yellow powder
Storage condition-20°C, protect from light, stored under nitrogen
Product details

A-83-01 is a potent inhibitor of TGF-β type I receptor (ALK5-TD) with IC50 of 12 nM. A-83-01 also inhibits the transcription induced by activin/nodal type I receptor (ALK4-TD) and nodal type I receptor (ALK7-TD) with IC50 of 45 nM and 7.5 nM, respectively.

Solutions are unstable and should be fresh-prepared.


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