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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5 days	￥898.00	Visible after login	- +
2 mg	3-5 days	￥1438.00	Visible after login	- +
5 mg	3-5 days	￥2446.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

1 mg

3-5 days

￥898.00

Visible after login

- +

2 mg

3-5 days

￥1438.00

Visible after login

- +

5 mg

3-5 days

￥2446.00

Visible after login

- +

Product Overview

Product Name	Deruxtecan \| DS-8201a \| exatecan derivative \| DX 8951;
CAS	1599440-13-7
Formula	C52H56FN9O13
MW	1,034.05
MDL	MFCD31657445
Appearance	White to yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Deruxtecan is an ADC drug-linker conjugate composed of the cleavable glycine–glycine–phenylalanine–glycine tetrapeptide-based linker, a self-immolative amino methylene spacer, and a novel topoisomerase 1 inhibitor payload that is a derivative of exatecan (DX-8951).

Related literature

Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity.

PMID: 27166974 PMCID: PMC4946713 DOI: 10.1111/cas.12966

Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma with HER2/neu expression.

PMID: 36610380 PMCID: PMC10445234 DOI: 10.1016/j.ygyno.2022.12.018

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History

CL2739

Deruxtecan | DS-8201a | exatecan derivative | DX 8951;

1599440-13-7 99+%

Chemical safety data sheet(MSDS)