| Product Name | Darbufelone | CI-1004 |
|---|---|
| CAS | 139226-28-1 |
| Formula | C18H24N2O2S |
| MW | 332.46 |
| Appearance | White to off-white powder |
| Storage condition | -20°C, sealed storage, away from moisture |
| Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
|---|---|---|---|---|
| 5 mg | In-stock | ¥568.00 | Visible after login | |
| 10 mg | In-stock | ¥898.00 | Visible after login | |
| 25 mg | In-stock | ¥1436.00 | Visible after login |
| Product Name | Darbufelone | CI-1004 |
|---|---|
| CAS | 139226-28-1 |
| Formula | C18H24N2O2S |
| MW | 332.46 |
| Appearance | White to off-white powder |
| Storage condition | -20°C, sealed storage, away from moisture |
Darbufelone is a dual inhibitor of cellular PGF2α and LTB4 production. Darbufelone potently inhibits PGHS-2 (IC50= 0.19 μM) but is much less potent with PGHS-1 (IC50=20 μM).
PMID: 11412128 DOI: 10.1021/bi002343f
PMID: 20352217 DOI: 10.1007/s00280-009-1161-z