Ropivacaine hydrochloride | 98717-15-8

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Size

Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	Ropivacaine hydrochloride
CAS	98717-15-8
Formula	C17H26N2O·HCl
MW	310.86 \| 274.41(free)
Appearance	White to off-white powder
Storage condition	4°C, sealed storage, away from moisture

Product details

Ropivacaine hydrochloride is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese. Ropivacaine is also an inhibitor of K_2P (two-pore domain potassium channel) TREK-1 with an IC₅₀ of 402.7 μM in COS-7 cell's membrane. Ropivacaine is widely used for neuropathic pain management in vivo.

Related literature

Epidural sustained release ropivacaine prolongs anti-allodynia and anti-hyperalgesia in developing and established neuropathic pain.

PMID: 25617901 PMCID: PMC4305322 DOI: 10.1371/journal.pone.0117321

Ropivacaine: a review of its use in regional anaesthesia and acute pain management.

PMID: 16392884 DOI: 10.2165/00003495-200565180-00013

Ropivacaine Inhibits Pressure-Induced Lung Endothelial Hyperpermeability in Models of Acute Hypertension.

PMID: 30822427 DOI: 10.1016/j.lfs.2019.02.053

The inhibitory effects of bupivacaine, levobupivacaine, and ropivacaine on K2P (two-pore domain potassium) channel TREK-1.

PMID: 23797625 DOI: 10.1007/s00540-013-1661-1