Product Name | RapaLink-1 |
---|---|
CAS | 1887095-82-0 |
Formula | C91H138N12O24 |
MW | 1,784.14 |
Appearance | White to light yellow powder |
Storage condition | -20°C, sealed storage, away from moisture |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
---|---|---|---|---|
1 mg | 3-5days | ¥3980.00 | Visible after login |
Product Name | RapaLink-1 |
---|---|
CAS | 1887095-82-0 |
Formula | C91H138N12O24 |
MW | 1,784.14 |
Appearance | White to light yellow powder |
Storage condition | -20°C, sealed storage, away from moisture |
Rapalink-1 is a brain-permeable mTOR inhibitor that inhibits oxidative stress-induced DNA damage and senescence in ethanol-exposed endothelial cells, and inhibits the mTORC1-4E-BP1 pathway in mice.Rapalink-1 is used for the study of prostate cancer due to its anticancer activity.
A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma.
PMID: 28292440 PMCID: PMC5386178 DOI: 10.1016/j.ccell.2017.01.014
Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor.
PMID: 27279227 PMCID: PMC4902179 DOI: 10.1038/nature17963
PMID: 32232883 PMCID: PMC7226215 DOI: 10.1111/cas.14395