MK-2894

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5days	￥636.00	Visible after login	- +
2 mg	3-5days	￥1048.00	Visible after login	- +
5 mg	3-5days	￥1988.00	Visible after login	- +
10 mg	3-5days	￥3360.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

1 mg

3-5days

￥636.00

Visible after login

- +

2 mg

3-5days

￥1048.00

Visible after login

- +

5 mg

3-5days

￥1988.00

Visible after login

- +

10 mg

3-5days

￥3360.00

Visible after login

- +

Product Overview

Product Name	MK-2894
CAS	1006036-87-8
Formula	C25H22F3NO3S
MW	473.51
Appearance	White to light brown powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

MK-2894 is a potent, selective, orally active and high affinity (K_i=0.56 nM) full antagonist against E prostanoid receptor 4 (EP4 receptor) (IC₅₀=2.5 nM). MK-2894 possesses potent anti-inflammatory activity in animal models of pain/inflammation and can be used for the research of arthritis.

Related literature

The discovery of 4-{1-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic acid (MK-2894), a potent and selective prostaglandin E2 subtype 4 receptor antagonist.

PMID: 20163116 DOI: 10.1021/jm901771h

Structural features of subtype-selective EP receptor modulators.

PMID: 27506873 DOI: 10.1016/j.drudis.2016.08.003

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