| Product Name | Brigimadlin (Synonyms: BI 907828) | 
|---|---|
| CAS | 2095116-40-6 | 
| Formula | C31H25Cl2FN4O3 | 
| MW | 591.46 | 
| Appearance | White to off-white powder | 
| Storage condition | Store short-term at 0-4°C or long-term at -20°C in a dry, dark place. | 
| Size | Availability | Price(USD) | VIP Price (USD) | Quantity | 
|---|---|---|---|---|
| 1 mg | 3-5 days | ¥1388.00 | Visible after login | |
| 5 mg | 3-5 days | ¥3566.00 | Visible after login | 
| Product Name | Brigimadlin (Synonyms: BI 907828) | 
|---|---|
| CAS | 2095116-40-6 | 
| Formula | C31H25Cl2FN4O3 | 
| MW | 591.46 | 
| Appearance | White to off-white powder | 
| Storage condition | Store short-term at 0-4°C or long-term at -20°C in a dry, dark place. | 
Brigimadlin (BI 907828) is a potent, orally active MDM2-p53 antagonist that inhibits the E3 ubiquitin-protein ligase MDM2, thereby preventing its negative regulation of the tumor suppressor p53. It's used in research for metastatic bile duct cancer, pancreatic cancer, lung adenocarcinoma, and bladder cancer.
PMID: 36521007 PMCID: PMC10158121 DOI: 10.1093/neuonc/noac271
PMID: 38214149 DOI: 10.2217/fon-2023-0963