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Product Overview

Product Name	Anti-Human CD3xCD20 Bispecific Antibody (Mosunetuzumab; BTCT-4465A； R07030816；CD20-TDB; RG7828; CD20 CD3 bispecific antibody.)
CAS	1905409-39-3
Storage condition	store at -20°C

Product details

Mosunetuzumab is a humanized bispecific antibody that targets CD20 on B cells and CD3 on T cells, redirecting T-cell cytotoxicity to kill malignant B cells. This IgG1 TDB antibody is being studied for treating relapsed/refractory B-cell non-Hodgkin lymphomas.

Related literature

Single-Agent Mosunetuzumab Shows Durable Complete Responses in Patients With Relapsed or Refractory B-Cell Lymphomas: Phase I Dose-Escalation Study.

PMID: 34914545 PMCID: PMC8824395 DOI: 10.1200/JCO.21.00931

A Preclinical Population Pharmacokinetic Model for Anti-CD20/CD3 T-Cell-Dependent Bispecific Antibodies.

PMID: 29351372 PMCID: PMC5944627 DOI: 10.1111/cts.12535

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