Product Name | Ailanthone |
---|---|
CAS | 981-15-7 |
Formula | C20H24O7 |
MW | 376.40 |
Appearance | White to off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
---|---|---|---|---|
1 mg | 3-5days | ¥336.00 | Visible after login | |
2 mg | 3-5days | ¥476.00 | Visible after login | |
5 mg | 3-5days | ¥688.00 | Visible after login |
Product Name | Ailanthone |
---|---|
CAS | 981-15-7 |
Formula | C20H24O7 |
MW | 376.40 |
Appearance | White to off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Ailanthone (Δ13-Dehydrochaparrinone) is a potent inhibitor of both full-length androgen receptor (AR) (IC50=69 nM) and constitutively active truncated AR splice variants (AR1-651 IC50=309 nM).
Ailanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer.
PMID: 27959342 PMCID: PMC5159881 DOI: 10.1038/ncomms13122
Sci Rep. 2015 Nov 3;5:16185.