Drug-Linker Conjugates for ADC

N-((S)-10-苄基-1-(((1S,9S)-9-乙基-5-氟-9-羟基-4-甲基-10,13-二氧代-2,3,9,10,13,15-六氢-1H,12H-苯并[de]吡喃并[3',4':6,7]吲哚嗪并[1,2-b]喹啉-1-基)氨基)-1,6,9,12,15-五氧代-3-氧杂-5,8,11,14-四氮杂十六烷-16-基)-6-(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)己酰胺;德鲁替康

Deruxtecan | DS-8201a | exatecan derivative | DX 8951;

3-5 days 99+%

Sulfo-PDBA-DM4

Sulfo-PDBA-DM4

- 98+%

sulfo-SPDB-DM4

sulfo-SPDB-DM4

- 95+%

特司林

Tesirine | SG3249

3-5days 95+%

坎妥珠单抗

Cantuzumab

3-5days 95+%

Vc-seco-DUBA (SYD985)

Vc-seco-DUBA (SYD985)

- 95+%

4-((S)-2-((S)-2-(6-(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)己酰胺)-3-甲基丁酰胺)-5-脲基戊酰胺)苄基((S)-1-(((S)-1-(((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-羟基-1-苯丙烷-2-基)氨基)-1-甲氧基-2-甲基-3-氧代丙基）吡咯烷-1-基)-3-甲氧基-5-甲基-1-氧代庚-4-基)(甲基)氨基)-3-甲基-1-氧代丁烷-2-基)氨基)-3-甲基-1-氧代丁烷-2-基)(甲基)氨基甲酸酯

VcMMAE; Maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl-monomethyl auristatin E; Mc-Val-Cit-PAB-MMAE

- 98+%

赛妥珠单抗-格卫替康;沙西妥珠单抗戈维替康

Anti-Trop2 (sacituzumab govitecan biosimilar) mAb

3-5days 98+%

吉妥珠单抗奥佐米星

Anti-CD33 (gemtuzumab ozogamicin biosimilar) mAb

3-5days 95+%