| Product Name | Y-27632 (free base) |
|---|---|
| CAS | 146986-50-7 |
| Formula | C14H21N3O |
| MW | 247.34 |
| Appearance | White to off-white powder |
| Storage condition | -20°C, protect from light, stored under nitrogen |
| Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
|---|---|---|---|---|
| 5 mg | In-stock | ¥556.00 | Visible after login | |
| 10 mg | In-stock | ¥898.00 | Visible after login | |
| 25 mg | In-stock | ¥1436.00 | Visible after login |
| Product Name | Y-27632 (free base) |
|---|---|
| CAS | 146986-50-7 |
| Formula | C14H21N3O |
| MW | 247.34 |
| Appearance | White to off-white powder |
| Storage condition | -20°C, protect from light, stored under nitrogen |
Y-27632 is a potent and selective inhibitor of ROCK1 (p160ROCK) with IC50 of 140 nM in a cell-free assay, it exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.
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PMID: 27591478 DOI: 10.1016/j.scr.2016.07.009