Laduviglusib trihydrochloride | CHIR-99021 Trihydrochloride

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Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	Laduviglusib trihydrochloride \| CHIR-99021 Trihydrochloride
CAS	1782235-14-6
Formula	C22H18Cl2N8·3HCl
MW	574.72
Appearance	White to light yellow powder
Storage condition	4°C, sealed storage, away from moisture

Product details

Laduviglusib (CHIR-99021) trihydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib trihydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib trihydrochloride is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib trihydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib trihydrochloride induces autophagy.

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