Home > Category > Signaling Pathways > DNA Damage/DNA Repair > Topoisomerase > Irinotecan hydrochloride(Synonyms: (+)-Irinotecan hydrochloride; CPT-11 hydrochloride; VAL-413)

(S)-4,11-二乙基-4-羟基-3,14-二氧代-3,4,12,14-四氢-1H-吡喃并[3',4';6,7]吲哚并[1,2-b]喹啉-9-基[1,4'-联哌啶]-1'-羧酸盐酸盐; 伊立替康盐酸盐

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Catalog No：CL1044A CAS No.：100286-90-6 MDLNo：MFCD01862255 Formula：C33H39ClN4O6 MW：623.14

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Product Overview

Product Name	Irinotecan hydrochloride(Synonyms: (+)-Irinotecan hydrochloride; CPT-11 hydrochloride; VAL-413)
CAS	100286-90-6
Formula	C33H39ClN4O6
MW	623.14
MDL	MFCD01862255
Appearance	White to yellow powder
Storage condition	4°C, sealed storage, away from moisture

Product details

Irinotecan hydrochloride ((+)-Irinotecan hydrochloride) is a topoisomerase I inhibitor mainly used to treat colon cancer and rectal cancer.

Related literature

Thrombospondin-1 plus irinotecan: a novel antiangiogenic-chemotherapeutic combination that inhibits the growth of advanced human colon tumor xenografts in mice.

PMID: 14658007 DOI: 10.1007/s00280-003-0712-y

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Antitumoral effect of irinotecan (CPT-11) on an experimental model of malignant neuroectodermal tumor.

J Neurooncol. 2002 Feb;56(3):219-26.

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Determinants of the cytotoxicity of irinotecan in two human colorectal tumor cell lines.

PMID: 11914913 DOI: 10.1007/s00280-001-0416-0

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Irinotecan Hydrochloride Trihydrate (Synonyms: Irinotecan (CPT-11) HCl Trihydrate;(+)-Irinotecan hydrochloride trihydrate; CPT-11 hydrochloride trihydrate)

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History

Irinotecan hydrochloride(Synonyms: (+)-Irinotecan hydrochloride; CPT-11 hydrochloride; VAL-413)

100286-90-6 98+%