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CP-547632 TFA

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Catalog No：CL1991B CAS No.：2805804-54-8 MDLNo： Formula：C20H24BrF2N5O3S·C2HF3O2 MW：646.43 | 532.40(free)

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Product Overview

Product Name	CP-547632 TFA
CAS	2805804-54-8
Formula	C20H24BrF2N5O3S·C2HF3O2
MW	646.43 \| 532.40(free)
Appearance	Off-white to light yellow powder
Storage condition	4°C, stored under nitrogen, away from moisture

Product details

CP-547632 TFA is an orally active, ATP-competitive and potent VEGFR-2 and FGF kinases inhibitor with IC₅₀s of 11 nM and 9 nM, respectively. CP-547632 TFA is selective for VEGFR2 and bFGF over EGFR, PDGFRβ, and related tyrosine kinases (TKs). CP-547632 TFA has antitumor efficacy.

Related literature

Pharmacological characterization of CP-547,632, a novel vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for cancer therapy.

PMID: 14612527

CL1991A

CP-547632 hydrochloride

252003-71-7 98+%

CL1991

CP-547632 (Synonyms: PAN-90806; CP-632; OSI-632)

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