| Product Name | PF-03814735 |
|---|---|
| CAS | 942487-16-3 |
| Formula | C23H25F3N6O2 |
| MW | 474.48 |
| Appearance | White to off-white powder |
| Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
| Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
|---|---|---|---|---|
| 1 mg | 3-5days | ¥650.00 | Visible after login | |
| 10 mg | 3-5days | ¥3200.00 | Visible after login | |
| 5 mg | 3-5days | ¥1850.00 | Visible after login |
| Product Name | PF-03814735 |
|---|---|
| CAS | 942487-16-3 |
| Formula | C23H25F3N6O2 |
| MW | 474.48 |
| Appearance | White to off-white powder |
| Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
PF-03814735 (PF03814735) is a reversible, orally bioavailable, and ATP-competitive inhibitor of Aurora A/B kinases with potential antitumor activity. It inhibits Aurora A/B with IC50of 0.8 nM and 5 nM, respectively. PF-03814735 showed less potency against Flt3, FAK, TrkA, Met and FGFR1. It exhibits potent in vitro antiproliferative activity and high in vivo antitumor efficacy.