| Product Name | Delgocitinib | JTE-052 | 
|---|---|
| CAS | 1263774-59-9 | 
| Formula | C16H18N6O | 
| MW | 310.35 | 
| Appearance | White to off-white powder | 
| Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). | 
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| Product Name | Delgocitinib | JTE-052 | 
|---|---|
| CAS | 1263774-59-9 | 
| Formula | C16H18N6O | 
| MW | 310.35 | 
| Appearance | White to off-white powder | 
| Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). | 
Delgocitinib, also known as LEO-124249 and JTE052, is a potent and selective JAK inhibitor. JTE-052 reduces skin inflammation and ameliorates chronic dermatitis in rodent models: Comparison with conventional therapeutic agents. JTE-052 regulates contact hypersensitivity by downmodulating T cell activation and differentiation. Delgocitinib has been shown to be effective and well-tolerated in human clinical trials and has recently been approved in Japan for the treatment of atopic dermatitis as the first drug among Janus kinase inhibitors.