PT-2385

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Availability

Price(USD)

VIP Price (USD)

Quantity

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Product Overview

Product Name	PT-2385
CAS	1672665-49-4
Formula	C17H12F3NO4S
MW	383.34
Appearance	White to off-white powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

PT2385 is an orally active, small molecule inhibitor of hypoxia inducible factor (HIF)-2alpha, with potential antineoplastic activity. Upon oral administration, HIF-2alpha inhibitor PT2385 allosterically binds to HIF-2alpha, thereby preventing HIF-2alpha heterodimerization and its subsequent binding to DNA. This results in decreased transcription and expression of HIF-2alpha downstream target genes, many of which regulate tumor cell growth and survival.
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History

CL2835

PT-2385

1672665-49-4 98+%

Chemical safety data sheet(MSDS)