Product Name | Poseltinib | HM71224 | LY3337641 |
---|---|
CAS | 1353552-97-2 |
Formula | C26H26N6O3 |
MW | 470.52 |
Appearance | Light yellow to yellow powder |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
---|---|---|---|---|
1 mg | 3-5days | ¥898.00 | Visible after login | |
5 mg | 3-5days | ¥1868.00 | Visible after login |
Product Name | Poseltinib | HM71224 | LY3337641 |
---|---|
CAS | 1353552-97-2 |
Formula | C26H26N6O3 |
MW | 470.52 |
Appearance | Light yellow to yellow powder |
Poseltinib (HM71224) is an orally active, selective, irreversible small molecule Bruton tyrosine kinase (BTK) inhibitor. With an IC50 of 1.95 nM. Poseltinib effectively inhibits the signaling mediated by B cell receptors (BCR), Fc receptors (FcR), and Toll-like receptors (TLR). Poseltinib has anti-inflammatory activity and can be used in the research of rheumatoid arthritis.