Home > Category > Signaling Pathways > Microbiology/Virology/Anti-infection > HCV Protease > Danoprevir (Synonyms: R7227; RO5190591; RG7227; ITMN-191;丹诺瑞韦)

(2R,6S,13aS,14aR,16aS,Z)-6-((叔丁氧羰基)氨基)-14a-((环丙基磺酰基)氨基甲酰基)-5,16-二氧代-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-十六氢环丙[e]吡咯并[1,2-a][1,4]二氮杂环十五-2-基 4-氟异吲哚啉-2-甲酸酯

ChemLeader 98+%

Catalog No：CL3100 CAS No.：850876-88-9 MDLNo：MFCD16038038 Formula：C35H46FN5O9S MW：731.83

Collect Share

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5days	￥388.00	Visible after login	- +
5 mg	3-5days	￥988.00	Visible after login	- +
10 mg	3-5days	￥1588.00	Visible after login	- +
25 mg	3-5days	￥2716.00	Visible after login	- +
50 mg	3-5days	￥3966.00	Visible after login	- +
100 mg	3-5days	￥5668.00	Visible after login	- +

Chemical safety data sheet(MSDS)

Download MSDS

Inquiry Add To Cart

Product Overview
Related documents
Product details
Related literature

Product Overview

Product Name	Danoprevir (Synonyms: R7227; RO5190591; RG7227; ITMN-191;丹诺瑞韦)
CAS	850876-88-9
Formula	C35H46FN5O9S
MW	731.83
MDL	MFCD16038038
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Danoprevir (RG7227) is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV).

Related literature

Genotype differences in susceptibility and resistance development of hepatitis C virus to protease inhibitors telaprevir (VX-950) and danoprevir (ITMN-191).

PMID: 21480315 DOI: 10.1002/hep.24172

Read more

Natural prevalence of hepatitis C virus variants with decreased sensitivity to NS3.4A protease inhibitors in treatment-naive subjects.

PMID: 18637752 DOI: 10.1086/591141

Read more

Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical trials, inhibit SARS-CoV-2 replication and its 3C-like protease.

PMID: 34052830 PMCID: PMC8164054 DOI: 10.1038/s41392-021-00628-x

Read more

Related

Sorry, no related items

History

Danoprevir (Synonyms: R7227; RO5190591; RG7227; ITMN-191;丹诺瑞韦)

850876-88-9 98+%

Dihexa (Synonyms: PNB-0408; N-hexanoic-Try-Ile-(6)-amino hexanoic amide; Hexanoyl-Tyr-Ile-Ahx-NH2)

1401708-83-5 98+%

5-Aminolevulinic acid hexyl ester Hydrochloride; Hexaminolevulinate Hydrochloride

140898-91-5 98+%