首页 > 产品目录 > 信号通路 > Immunology & Inflammation > Toll-like Receptor (TLR) (Toll样受体) > (R)-6-(N-(2-氯-4-氟苯基)氨磺酰基)环己-1-烯羧酸乙酯;瑞沙托维

(R)-6-(N-(2-氯-4-氟苯基)氨磺酰基)环己-1-烯羧酸乙酯;瑞沙托维

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Resatorvid (Synonyms: TAK-242; CLI-095;(R)-Ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate)

产品编号:CL1002 CAS No.:243984-11-4 MDLNo: 分子式:C15H17ClFNO4S 分子量:361.82
规格 库存 目录价 会员专享价 数量
5 mg 3-5days ¥898.00 登录后可见
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10 mg 3-5days ¥1288.00 登录后可见
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基本信息
英文名称 Resatorvid (Synonyms: TAK-242; CLI-095;(R)-Ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate)
中文名称(R)-6-(N-(2-氯-4-氟苯基)氨磺酰基)环己-1-烯羧酸乙酯;瑞沙托维
CAS号243984-11-4
分子式C15H17ClFNO4S
分子量361.82
外观Off-white to yellow solid
储存条件Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
产品详情

Resatorvid (TAK-242, CLI-095) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, blocking LPS-induced production of NO, TNF-α and IL-6 in macrophages with IC50 of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy.
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