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Y-27632

ChemLeader Purity:>99.5% | EE:100%

Y-27632 (free base)

产品编号：CL1003A CAS No.：146986-50-7 MDLNo： 分子式：C14H21N3O 分子量：247.34

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规格	库存	目录价	会员专享价	数量
5 mg	In-stock	￥556.00	登录后可见	- +
10 mg	In-stock	￥898.00	登录后可见	- +
25 mg	In-stock	￥1436.00	登录后可见	- +

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基本信息
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基本信息

英文名称	Y-27632 (free base)
中文名称	Y-27632
CAS号	146986-50-7
分子式	C14H21N3O
分子量	247.34
外观	White to off-white powder
储存条件	-20°C, protect from light, stored under nitrogen

产品详情

Y-27632 is a potent and selective inhibitor of ROCK1 (p160ROCK) with IC50 of 140 nM in a cell-free assay, it exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.
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相关文献

ROCK inhibitor primes human induced pluripotent stem cells to selectively differentiate towardsmesendodermal lineage via epithelial-mesenchymal transition-like modulation.

PMID: 27591478 DOI: 10.1016/j.scr.2016.07.009

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Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases.

PMID: 10779382

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Rho-associated coiled kinase inhibitor Y-27632 promotes neuronal-like differentiation of adult human adipose tissue-derived stem cells

PMID: 22964332

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146986-50-7 Purity:>99.5% | EE:100% In-stock