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库存

目录价

会员专享价

数量

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基本信息

英文名称	Amifostine
中文名称	氨磷汀
CAS号	20537-88-6
分子式	C5H15N2O3PS
分子量	214.22
MDL	MFCD00233058
外观	White to off-white powder
储存条件	Powder -20°C3 years ; 4°C 2 years ;\| In solvent -80°C 6 months ; -20°C 1 month

产品详情

Amifostine (WR2721) is a potent cytoprotective and radioprotective agent, selectively safeguarding normal tissues from chemotherapy and radiation-induced damage. It acts as a prodrug, activating to WR-1065 by alkaline phosphatase, which scavenges free radicals and protects cells. Amifostine also induces HIF-α1 and p53, key regulators in the cellular response to hypoxia and DNA damage. Its antiangiogenic properties, by modulating VEGF-A, suggest potential in inhibiting tumor vasculature. Recent studies highlight its renal toxicity reduction and explore PEGylation to enhance safety and efficacy, making Amifostine a versatile protector in cancer therapies.

氨磷汀

Amifostine

化学品安全说明书(MSDS)