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(Z)-3-(((4-(N-甲基-2-(4-甲基哌嗪-1-基)乙酰氨基)苯基)氨基)(苯基)亚甲基)-2-氧代吲哚啉-6-羧酸甲酯; 尼达尼布

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Nintedanib (Synonyms: BIBF 1120; Intedanib)

产品编号:CL1034 CAS No.:656247-17-5 MDLNo:MFCD11974012 分子式:C31H33N5O4 分子量:539.62
规格 库存 目录价 会员专享价 数量
500 mg In-stock ¥898.00 登录后可见
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1 g In-stock ¥1488.00 登录后可见
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基本信息
英文名称 Nintedanib (Synonyms: BIBF 1120; Intedanib)
中文名称(Z)-3-(((4-(N-甲基-2-(4-甲基哌嗪-1-基)乙酰氨基)苯基)氨基)(苯基)亚甲基)-2-氧代吲哚啉-6-羧酸甲酯; 尼达尼布
CAS号656247-17-5
分子式C31H33N5O4
分子量539.62
MDLMFCD11974012
外观Yellow crystalline powder
产品详情

Nintedanib, also known as BIBF 1120, is an orally bioavailable inhibitor of vascular endothelial growth factor receptor (VEGFR), fibroblast growth factor receptor (FGFR) and platelet derived growth factor receptor (PDGFR). Intedanib selectively binds to and inhibits vascular endothelial growth factor receptor (VEGFR), fibroblast growth factor receptor (FGFR) and platelet-derived growth factor receptor (PDGFR) tyrosine kinases, which may result in the induction of endothelial cell apoptosis; a reduction in tumor vasculature; and the inhibition of tumor cell proliferation and migration.
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