Dapagliflozin (BMS-512148; 达格列净) CAS: 461432-26-8

规格	库存	目录价	会员专享价	数量
100 mg	In-stock	￥566.00	登录后可见	- +
250 mg	In-stock	￥788.00	登录后可见	- +
500 mg	In-stock	￥1488.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

100 mg

In-stock

￥566.00

登录后可见

- +

250 mg

In-stock

￥788.00

登录后可见

- +

500 mg

In-stock

￥1488.00

登录后可见

- +

基本信息

英文名称	Dapagliflozin (BMS-512148; 达格列净)
中文名称	(2S,3R,4R,5S,6R)-2-(4-氯-3-(4-乙氧基苄基)苯基)-6-(羟甲基)四氢-2H-吡喃-3,4,5-三醇
CAS号	461432-26-8
分子式	C21H25ClO6
分子量	408.87
MDL	MFCD13182359
外观	White to off-white powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Dapagliflozin (formerly known as BMS-512148; trade names Farxiga in the US and Forxiga in the EU) is a potent and selective hSGLT2 (sodium-glucose transport proteins) inhibitor with anti-diabetic activity. It inhibits hSGLT2 with an EC50 of 1.1 nM, and exhibits1200-fold selectivity over hSGLT1. Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2) which are responsible for at least 90% of the glucose reabsorption in the kidney. Urine is the means by which blood glucose is expelled when this transporter mechanism is blocked.

(2S,3R,4R,5S,6R)-2-(4-氯-3-(4-乙氧基苄基)苯基)-6-(羟甲基)四氢-2H-吡喃-3,4,5-三醇

Dapagliflozin (BMS-512148; 达格列净)

化学品安全说明书(MSDS)

质检证书(COA)