| 英文名称 | Decernotinib (Synonyms: VX-509; VRT-831509) |
|---|---|
| 中文名称 | 德塞替尼 | 地诺替尼 | 迪西替尼 |
| CAS号 | 944842-54-0 |
| 分子式 | C18H19F3N6O |
| 分子量 | 392.38 |
| 外观 | White to off-white powder |
| 储存条件 | 4°C, protect from light, stored under nitrogen |
| 英文名称 | Decernotinib (Synonyms: VX-509; VRT-831509) |
|---|---|
| 中文名称 | 德塞替尼 | 地诺替尼 | 迪西替尼 |
| CAS号 | 944842-54-0 |
| 分子式 | C18H19F3N6O |
| 分子量 | 392.38 |
| 外观 | White to off-white powder |
| 储存条件 | 4°C, protect from light, stored under nitrogen |
Decernotinib (VX-509) is a potent and selective JAK3 inhibitor with Ki of 2.5 nM, >4-fold selectivity over JAK1, JAK2, and TYK2, respectively.
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PMID: 25762693 DOI: 10.1124/jpet.114.221176