Obeticholic Acid (Synonyms: INT-747; 6-ECDCA;6-Ethylchenodeoxycholic acid)；FXR agonist; CAS: 459789-99-2

规格	库存	目录价	会员专享价	数量
5 mg	In-stock	￥288.00	登录后可见	- +
10 mg	In-stock	￥468.00	登录后可见	- +
25 mg	In-stock	￥726.00	登录后可见	- +
50 mg	In-stock	￥1068.00	登录后可见	- +
100 mg	In-stock	￥1496.00	登录后可见	- +
250 mg	In-stock	￥2206.00	登录后可见	- +
500 mg	In-stock	￥3288.00	登录后可见	- +
1 g	In-stock	￥4800.00	登录后可见	- +
5 g	In-stock	￥11200.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

5 mg

In-stock

￥288.00

登录后可见

- +

10 mg

In-stock

￥468.00

登录后可见

- +

25 mg

In-stock

￥726.00

登录后可见

- +

50 mg

In-stock

￥1068.00

登录后可见

- +

100 mg

In-stock

￥1496.00

登录后可见

- +

250 mg

In-stock

￥2206.00

登录后可见

- +

500 mg

In-stock

￥3288.00

登录后可见

- +

1 g

In-stock

￥4800.00

登录后可见

- +

5 g

In-stock

￥11200.00

登录后可见

- +

基本信息

英文名称	Obeticholic Acid (Synonyms: INT-747; 6-ECDCA;6-Ethylchenodeoxycholic acid)
中文名称	(R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-乙基-3,7-二羟基-10,13-二甲基十六氢-1H-环戊二烯并[a]菲-17-基)戊酸; 奥贝胆酸
CAS号	459789-99-2
分子式	C26H44O4
分子量	420.63
MDL	MFCD16621104
外观	White to off-white powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Obeticholic acid (OCA), a potent FXR agonist with an EC50 of 99 nM, targets bile acid synthesis and exhibits anticholeretic and anti-inflammatory effects, inducing autophagy. Its bioactivity is optimized through ROS-responsive nanoparticle delivery, enhancing liver targeting and reducing hepatotoxicity, offering a promising therapeutic strategy for cholestatic liver diseases.

(R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-乙基-3,7-二羟基-10,13-二甲基十六氢-1H-环戊二烯并[a]菲-17-基)戊酸; 奥贝胆酸

Obeticholic Acid (Synonyms: INT-747; 6-ECDCA;6-Ethylchenodeoxycholic acid)

化学品安全说明书(MSDS)

质检证书(COA)