Alectinib Hydrochloride | CH5424802 Hydrochloride | RO5424802 Hydrochloride | AF-802 Hydrochloride | Alectinib HCl

规格	库存	目录价	会员专享价	数量
暂无牌价信息，您可以发送询价，我们会尽快给你回复。

规格

库存

目录价

会员专享价

数量

暂无牌价信息，您可以发送询价，我们会尽快给你回复。

基本信息

英文名称	Alectinib Hydrochloride (Synonyms: CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride;Alectinib HCl)
中文名称	9-乙基-6,6-二甲基-8-(4-吗啉-4-基哌啶-1-基)-11-氧代-5H-苯并[b]咔唑-3-腈盐酸盐;艾乐替尼盐酸盐;盐酸阿来替尼
CAS号	1256589-74-8
分子式	C30H35ClN4O2
分子量	519.08
MDL	MFCD27987893

产品详情

Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.

9-乙基-6,6-二甲基-8-(4-吗啉-4-基哌啶-1-基)-11-氧代-5H-苯并[b]咔唑-3-腈盐酸盐;艾乐替尼盐酸盐;盐酸阿来替尼

Alectinib Hydrochloride (Synonyms: CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride;Alectinib HCl)

化学品安全说明书(MSDS)