Adezmapimod Hydrochloride | SB 203580 Hydrochloride | RWJ 64809 Hydrochloride

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规格

库存

目录价

会员专享价

数量

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基本信息

英文名称	Adezmapimod Hydrochloride (Synonyms: SB 203580 hydrochloride; RWJ 64809 hydrochloride)
中文名称	Adezmapimod Hydrochloride \| SB 203580 Hydrochloride \| RWJ 64809 Hydrochloride
CAS号	869185-85-3
分子式	C21H17ClFN3OS
分子量	413.90
外观	Light yellow to yellow powder
储存条件	4°C, sealed storage, away from moisture

产品详情

Adezmapimod (SB 203580; RWJ 64809) hydrochloride is a selective and ATP-competitive p38 MAPK inhibitor with IC₅₀s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. Adezmapimod hydrochloride inhibits LCK, GSK3β and PKBα with IC₅₀s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod hydrochloride does not disrupt JNK activity and is an autophagy and mitophagy activator.

Adezmapimod Hydrochloride | SB 203580 Hydrochloride | RWJ 64809 Hydrochloride

Adezmapimod Hydrochloride (Synonyms: SB 203580 hydrochloride; RWJ 64809 hydrochloride)

化学品安全说明书(MSDS)