Vatalanib Dihydrochloride | Vatalanib 2HCl |CAS 212141-51-0

规格	库存	目录价	会员专享价	数量
20 mg	In-stock	￥408.00	登录后可见	- +
50 mg	In-stock	￥472.00	登录后可见	- +
100 mg	In-stock	￥678.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

20 mg

In-stock

￥408.00

登录后可见

- +

50 mg

In-stock

￥472.00

登录后可见

- +

100 mg

In-stock

￥678.00

登录后可见

- +

基本信息

英文名称	Vatalanib Dihydrochloride \| Vatalanib 2HCl
中文名称	瓦他拉尼二盐酸盐
CAS号	212141-51-0
分子式	C20H17Cl3N4
分子量	419.73
外观	Off-white to pink powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Vatalanib (PTK787 or ZK-222584, cpg-79787 2HCl) 2HCl is a novel, potent and orally bioavailable inhibitor of VEGFR2/KDR with potential anticancer activity. In a cell-free experiment, it inhibits VEGFR2/KDR with an IC50 of 37 nM, is less effective against VEGFR1/Flt-1, and is 18-fold more potent against VEGFR3/Flt-4. With strong anti-proliferative activity in vitro and strong antitumor efficaciousness in vivo, it is an anilinophthalazine analog. The protein kinase domains of VEGFR 1 and 2 are bound by vatalanib, which then inhibits them. The PDGF receptor, c-Kit, and c-Fms are among the related receptor tyrosine kinases that this agent binds to and inhibits.

瓦他拉尼二盐酸盐

Vatalanib Dihydrochloride | Vatalanib 2HCl

化学品安全说明书(MSDS)

质检证书(COA)