Romidepsin (Synonyms: FK 228; FR 901228; NSC 630176)； CAS: 128517-07-7

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基本信息

英文名称	Romidepsin (Synonyms: FK 228; FR 901228; NSC 630176; Depsipeptide)
中文名称	(1S,4S,7Z,10S,16E,21R)-7-亚乙基-4,21-二异丙基-2-氧杂-12,13-二硫杂-5,8,20,23-四氮杂双环[8.7.6]二十三烷-16-烯-3,6,9,19,22-五酮; 罗米地辛
CAS号	128517-07-7
分子式	C24H36N4O6S2
分子量	540.70
MDL	MFCD18433404
外观	White to off-white powder

产品详情

Romidepsin (FR 901228) is an HDAC inhibitor targeting HDAC1/2/4/6 with IC50 values of 36/47/510/1400 nM. It has antitumor activity and is used to treat peripheral and cutaneous T-cell lymphomas.Romidepsin (FK 228), derived from Chromobacterium violaceum, induces G2/M cell cycle arrest and apoptosis.
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(1S,4S,7Z,10S,16E,21R)-7-亚乙基-4,21-二异丙基-2-氧杂-12,13-二硫杂-5,8,20,23-四氮杂双环[8.7.6]二十三烷-16-烯-3,6,9,19,22-五酮; 罗米地辛

Romidepsin (Synonyms: FK 228; FR 901228; NSC 630176; Depsipeptide)

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