Gemcitabine Base | LY 188011 | NSC 613327 | CAS 95058-81-4

规格	库存	目录价	会员专享价	数量
500 mg	In-stock	￥578.00	登录后可见	- +
1 g	In-stock	￥858.00	登录后可见	- +

基本信息

英文名称	Gemcitabine (Synonyms: LY 188011;Gemcitabine Base;NSC 613327)
中文名称	吉西他滨
CAS号	95058-81-4
分子式	C9H11F2N3O4
分子量	263.2
MDL	MFCD00869720
外观	White to off-white powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

安全信息

产品详情

Gemcitabine (formerly LY-188011, NSC-613327; LY188011, NSC613327; dFdC; dFdCyd), an approved antimetabolite anticancer drug, is a potent DNA synthesis inhibitor with potential antineoplastic activity. With IC50s of 50 nM, 40 nM, 18 nM, and 12 nM, respectively, it suppresses the growth of PANC1, MIAPaCa2, BxPC3, and Capan2 cells. Difluorodeoxycytidine di- and triphosphate (dFdCDP, dFdCTP) are the active metabolites of gemcitabine that are produced intracellularly. The deoxynucleotide pool available for DNA synthesis is reduced when dFdCDP inhibits ribonucleotide reductase.
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吉西他滨

Gemcitabine (Synonyms: LY 188011;Gemcitabine Base;NSC 613327)

化学品安全说明书(MSDS)

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