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(S)-3-(4-羟基苯基)苯并二氢吡喃-7-醇 | (S)-雌马酚

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(-)-(S)-Equol | AUS 131 | SE 5OH

产品编号：CL2040 CAS No.：531-95-3 MDLNo： 分子式：C15H14O3 分子量：242.27

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基本信息
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基本信息

英文名称	(-)-(S)-Equol \| AUS 131 \| SE 5OH
中文名称	(S)-3-(4-羟基苯基)苯并二氢吡喃-7-醇 \| (S)-雌马酚
CAS号	531-95-3
分子式	C15H14O3
分子量	242.27
外观	Off white or pale yellow solid
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

(-)-(S)-Equol is a high affinity ligand for estrogen receptor β with a Ki of 0.73 nM.-). -(S)-Equolis a non-steroidal Estrogen generated when soybean products are metabolized by certain bacteria in the intestines. Equol is an antagonist of dihydrotestosterone and has implications for prostate cancer and other androgen-mediated pathologies.

相关文献

S-equol, a Secondary Metabolite of Natural Anticancer Isoflavone Daidzein, Inhibits Prostate Cancer Growth In Vitro and In Vivo, Though Activating the Akt/FOXO3a Pathway.

PMID: 26638886 DOI: 10.2174/1568009616666151207105720

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S-equol nantioselectively activates cAMP-protein kinase A signaling and reduces alloxan-induced cell death in INS-1 pancreatic β-cells.

PMID: 25297619

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S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora.

PMID: 15883431 DOI: 10.1093/ajcn/81.5.1072

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