英文名称 | Rebamipide(OPC-12759;Proamipide) |
---|---|
中文名称 | 瑞巴派特 |
CAS号 | 90098-04-7 |
分子式 | C19H15ClN2O4 |
分子量 | 370.79 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名称 | Rebamipide(OPC-12759;Proamipide) |
---|---|
中文名称 | 瑞巴派特 |
CAS号 | 90098-04-7 |
分子式 | C19H15ClN2O4 |
分子量 | 370.79 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Rebamipide (OPC12759) is an orally bioactive gastroprotective agent. Rebamipide enhances the production of endogenous PGs (especially intragastric PGE2) by inducing the expression of COX-2, thereby protecting the gastric mucosa from injury. Rebamipide also has antiproliferation activity against gastric cancer/tumor cells. Rebamipide can be used for mucosal protection, gastroduodenal ulcer, gastritis and gastric cancer research.