| 英文名称 | Ritonavir (ABT 538) |
|---|---|
| 中文名称 | 利托那韦 |
| CAS号 | 155213-67-5 |
| 分子式 | C37H48N6O5S2 |
| 分子量 | 720.94 |
| 外观 | White to off-white powder |
| 储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
| 英文名称 | Ritonavir (ABT 538) |
|---|---|
| 中文名称 | 利托那韦 |
| CAS号 | 155213-67-5 |
| 分子式 | C37H48N6O5S2 |
| 分子量 | 720.94 |
| 外观 | White to off-white powder |
| 储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Ritonavir is an inhibitor of HIV-1 protease used to treat HIV infection and AIDS. It is widely used as a booster of other protease inhibitors.
Ritonavir is a Cytochrome P450 3A and Protease Inhibitor; Also inhibits Cytochrome P450 2D6, P-Glycoprotein and induces Cytochrome P450 2C19, Cytochrome P450 1A2, Cytochrome P450 2C9, Cytochrome P450 2B6 and UDP Glucuronosyltransferases. Ritonavir induces apoptosis.