Nigericin Sodium Salt

规格	库存	目录价	会员专享价	数量
5 mg	In-stock	￥466.00	登录后可见	- +
10 mg	In-stock	￥766.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

5 mg

In-stock

￥466.00

登录后可见

- +

10 mg

In-stock

￥766.00

登录后可见

- +

基本信息

英文名称	Nigericin Sodium Salt
中文名称	尼日利亚菌素钠盐
CAS号	28643-80-3
分子式	C40H67NaO11
分子量	746.94
外观	White to off-white powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Nigericin is a cationic ionophore that inhibits Golgi function and suppresses growth of gram positive bacteria. It also prevents viral activation and triggers activation of the NALP3 inflammasome. Nigericin acts as an H+, K+, Pb2+ ionophore. Most commonly it is an antiporter of H+ and K+. In the past nigericin was used as an antibiotic active against gram positive bacteria. It inhibits the Golgi functions in Eukaryotic cells. Its ability to induce K+ efflux also makes it a potent activator of the NLRP3 inflammasome.

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