CO-1686 (Rociletinib)

规格	库存	目录价	会员专享价	数量
20 mg	In-stock	￥560.00	登录后可见	- +
50 mg	In-stock	￥860.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

20 mg

In-stock

￥560.00

登录后可见

- +

50 mg

In-stock

￥860.00

登录后可见

- +

基本信息

英文名称	CO-1686 (Rociletinib)
中文名称	诺司替尼 \| 罗乐替尼\| 罗西替尼
CAS号	1374640-70-6
分子式	C27H28F3N7O3
分子量	555.55
外观	White to off-white powder

产品详情

Rociletinib, also known as AVL-301 and CO1686, is an orally available small molecule, irreversible inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. EGFR inhibitor CO-1686 binds to and inhibits mutant forms of EGFR, including T790M, thereby leading to cell death of resistant tumor cells. Compared to other EGFR inhibitors, CO-1686 inhibits T790M, a secondary acquired resistance mutation, as well as other mutant EGFRs and may have therapeutic benefits in tumors with T790M-mediated resistance to other EGFR tyrosine kinase inhibitors.

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CL2330

诺司替尼 | 罗乐替尼| 罗西替尼

1374640-70-6 98+% In-stock

￥560.00 20 mg