ABT-737

规格	库存	目录价	会员专享价	数量
5 mg	In-stock	￥480.00	登录后可见	- +
10 mg	In-stock	￥760.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

5 mg

In-stock

￥480.00

登录后可见

- +

10 mg

In-stock

￥760.00

登录后可见

- +

基本信息

英文名称	ABT-737
中文名称	ABT-737
CAS号	852808-04-9
分子式	C42H45ClN6O5S2
分子量	813.43
外观	Yellow to orange powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

ABT-737 is an orally available inhibitor of the nuclear enzymes poly(ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. Upon administration, ABT-767 selectively binds to PARP 1 and 2, thereby preventing repair of damaged DNA via the base excision repair (BER) pathway. This agent enhances the accumulation of DNA strand breaks and promotes genomic instability eventually leading to apoptosis. ABT-767 may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell chemo- and radioresistance.

ABT-737

ABT-737

化学品安全说明书(MSDS)

质检证书(COA)