Navitoclax | ABT-263 | 923564-51-6

规格	库存	目录价	会员专享价	数量
5 mg	In-stock	￥480.00	登录后可见	- +
10 mg	In-stock	￥760.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

5 mg

In-stock

￥480.00

登录后可见

- +

10 mg

In-stock

￥760.00

登录后可见

- +

基本信息

英文名称	Navitoclax (Synonyms: ABT-263; A-855071)
中文名称	(R)-4-(4-((4'-氯-4,4-二甲基-3,4,5,6-四氢-[1,1'-联苯]-2-基)甲基)哌嗪-1-基)-N-((4-((4-吗啉-1-(苯硫基)丁烷-2-基)氨基)-3-((三氟甲基)磺酰)苯基)磺酰)苯甲酰胺
CAS号	923564-51-6
分子式	C47H55ClF3N5O6S3
分子量	974.61
外观	White to light yellow powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Navitoclax, also known as ABT-263, is an orally bioavailable, synthetic small-molecule antagonist of a subset of the B-cell leukemia 2 (Bcl-2) family of proteins with potential antineoplastic activity. ABT-263 selectively binds to apoptosis suppressor proteins Bcl-2, Bcl-XL, and Bcl-w and prevents their binding to the apoptotic effectors Bax and Bak proteins, which may trigger apoptosis in tumor cells overexpressing Bcl-2, Bcl-XL, and Bcl-w.
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CL2346

(R)-4-(4-((4'-氯-4,4-二甲基-3,4,5,6-四氢-[1,1'-联苯]-2-基)甲基)哌嗪-1-基)-N-((4-((4-吗啉-1-(苯硫基)丁烷-2-基)氨基)-3-((三氟甲基)磺酰)苯基)磺酰)苯甲酰胺

923564-51-6 98+% In-stock

￥480.00 5 mg