buy MG-132 | MG-132 supplier | purchase MG-132 | MG-132 cost | MG-132 manufacturer | order MG-132 | MG-132 distributor； (Synonyms: Z-Leu-Leu-Leu-al; MG132); CAS: 133407-82-6

规格	库存	目录价	会员专享价	数量
5 mg	In-stock	￥276.00	登录后可见	- +
10 mg	In-stock	￥466.00	登录后可见	- +
25 mg	In-stock	￥746.00	登录后可见	- +
50 mg	In-stock	￥1198.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

5 mg

In-stock

￥276.00

登录后可见

- +

10 mg

In-stock

￥466.00

登录后可见

- +

25 mg

In-stock

￥746.00

登录后可见

- +

50 mg

In-stock

￥1198.00

登录后可见

- +

基本信息

英文名称	MG-132 (Synonyms: Z-Leu-Leu-Leu-al; MG132)
中文名称	N-[(苄氧基)羰基]-L-亮氨酰-N-[(1S)-1-甲酰基-3-甲基丁基]-L-亮氨酰胺
CAS号	133407-82-6
分子式	C26H41N3O5
分子量	475.62
MDL	MFCD00674886
外观	White to yellow powder
储存条件	Store short-term at 0-4°C or long-term at -20°C in a dry, dark place.

产品详情

MG-132, a potent proteasome and calpain inhibitor, boasts IC50s of 100 nM and 1.2 μM, respectively. This peptide aldehyde effectively halts the 26S proteasome complex's proteolytic activity. Beyond its inhibitory role, MG-132 activates autophagy and triggers apoptosis. Studies reveal that MG-132 can activate autophagy in vascular smooth muscle cells, inhibiting senescence through the PI3K/AKT/mTOR pathway. It also induces apoptosis in a cell cycle-dependent manner, highlighting its multifaceted bioactivity in cellular regulation.

N-[(苄氧基)羰基]-L-亮氨酰-N-[(1S)-1-甲酰基-3-甲基丁基]-L-亮氨酰胺

MG-132 (Synonyms: Z-Leu-Leu-Leu-al; MG132)

化学品安全说明书(MSDS)

质检证书(COA)