| 英文名称 | SGX-523 |
|---|---|
| 中文名称 | 6-[[6-(1-甲基-1H-吡唑-4-基)-1,2,4-三唑并[4,3-b]哒嗪-3-基]硫基]喹啉 |
| CAS号 | 1022150-57-7 |
| 分子式 | C18H13N7S |
| 分子量 | 359.41 |
| 外观 | Light yellow to yellow powder |
| 储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
| 英文名称 | SGX-523 |
|---|---|
| 中文名称 | 6-[[6-(1-甲基-1H-吡唑-4-基)-1,2,4-三唑并[4,3-b]哒嗪-3-基]硫基]喹啉 |
| CAS号 | 1022150-57-7 |
| 分子式 | C18H13N7S |
| 分子量 | 359.41 |
| 外观 | Light yellow to yellow powder |
| 储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
SGX523 is an exquisitely selective and ATP-competitive MET inhibitor. SGX523 potently inhibits MET with an IC50 of 4 nM and is >1,000-fold selective versus other protein kinases. Antitumor activity.
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PMID: 19934279 DOI: 10.1158/1535-7163.MCT-09-0477