Telaglenastat | CB-839 | 1439399-58-2

规格	库存	目录价	会员专享价	数量
5 mg	3-5days	￥578.00	登录后可见	- +
10 mg	3-5days	￥1088.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

5 mg

3-5days

￥578.00

登录后可见

- +

10 mg

3-5days

￥1088.00

登录后可见

- +

基本信息

英文名称	Telaglenastat \| CB-839
中文名称	CB-839
CAS号	1439399-58-2
分子式	C26H24F3N7O3S
分子量	571.57
外观	Off-white to yellow powder
储存条件	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

产品详情

Telaglenastat (CB-839) is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC₅₀s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat inuduces autophagy and has antitumor activity.

CB-839

Telaglenastat | CB-839

化学品安全说明书(MSDS)