英文名称 | Zotepine |
---|---|
中文名称 | 佐替平 | 唑替平 | 泽坦平 |
CAS号 | 26615-21-4 |
分子式 | C18H18ClNOS |
分子量 | 331.86 |
外观 | White to off-white powder |
储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
英文名称 | Zotepine |
---|---|
中文名称 | 佐替平 | 唑替平 | 泽坦平 |
CAS号 | 26615-21-4 |
分子式 | C18H18ClNOS |
分子量 | 331.86 |
外观 | White to off-white powder |
储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM and 8 nM, respectively. Zotepine exhibits antidepressive and anxiolytic effects in vivo.