Dasabuvir (ABT-333)

规格	库存	目录价	会员专享价	数量
10 mg	In-stock	￥600.00	登录后可见	- +
25 mg	In-stock	￥980.00	登录后可见	- +
50 mg	In-stock	￥1568.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

10 mg

In-stock

￥600.00

登录后可见

- +

25 mg

In-stock

￥980.00

登录后可见

- +

50 mg

In-stock

￥1568.00

登录后可见

- +

基本信息

英文名称	Dasabuvir \| ABT-333
中文名称	达萨布韦 \| 达塞布韦
CAS号	1132935-63-7
分子式	C26H27N3O5S
分子量	493.57
外观	White to yellow powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Dasabuvir (formerly known as ABT-333; ABT333; trade name Exviera, Viekira Pak, Viekira XR) is a nonnucleoside inhibitor of the RNA-dependent RNA polymerase encoded by the hepatitis C virus (HCV) NS5B gene. It inhibited recombinant NS5B polymerases derived from HCV genotype 1a and 1b clinical isolates, with IC50 values between 2.2 and 10.7 nM, and was at least 7,000-fold selective for the inhibition of HCV genotype 1 polymerases over human/mammalian polymerases. Dasabuvir is an FDA approved antiviral medication for the treatment of hepatitis C. It is often used together with the combination medication ombitasvir/paritaprevir/ritonavir specifically for hepatitis C virus (HCV) type 1.