Linsitinib | OSI-906 | 867160-71-2

规格	库存	目录价	会员专享价	数量
1 mg	3-5days	￥500.00	登录后可见	- +
5 mg	3-5days	￥980.00	登录后可见	- +
10 mg	3-5days	￥1600.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

1 mg

3-5days

￥500.00

登录后可见

- +

5 mg

3-5days

￥980.00

登录后可见

- +

10 mg

3-5days

￥1600.00

登录后可见

- +

基本信息

英文名称	Linsitinib (Synonyms: OSI-906; Cis-3-(8-Amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutan-1-ol)
中文名称	顺式-3-(8-氨基-1-(2-苯基喹啉-7-基)咪唑并[1,5-a]吡嗪-3-基)-1-甲基环丁醇; 林西替尼
CAS号	867160-71-2
分子式	C26H23N5O
分子量	421.49
外观	White to yellow powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Linsitinib (formerly OSI-906; OSI 906) is a firs-in-class, ATP-competitive and orally bioavailable dual inhibitor of and insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF-1R) with potential antitumor activity. It exhibits modest potency against InsR with an IC50 of 75 nM, and it has no activity against other kinases like Abl, ALK, BTK, EGFR, FGFR1/2, PKA, and so on. In cell-free assays, it inhibits IGF-1R with an IC50 of 35 nM.
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顺式-3-(8-氨基-1-(2-苯基喹啉-7-基)咪唑并[1,5-a]吡嗪-3-基)-1-甲基环丁醇; 林西替尼

Linsitinib (Synonyms: OSI-906; Cis-3-(8-Amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutan-1-ol)

化学品安全说明书(MSDS)