首页 > 产品目录 > 信号通路 > Protein Tyrosine Kinase/RTK > IGF-1R > Linsitinib (OSI-906)

Linsitinib (OSI-906)

ChemLeader 98+%

Linsitinib (OSI-906)

产品编号：CL2468 CAS No.：867160-71-2 MDLNo： 分子式：C26H23N5O 分子量：421.49

加入收藏分享给朋友

规格	库存	目录价	会员专享价	数量
1 mg	3-5days	￥500.00	登录后可见	- +
5 mg	3-5days	￥980.00	登录后可见	- +
10 mg	3-5days	￥1600.00	登录后可见	- +

化学品安全说明书(MSDS)

下载MSDS

发送询价加入购物车

基本信息
相关文档
产品详情
相关文献

基本信息

英文名称	Linsitinib (OSI-906)
中文名称	Linsitinib (OSI-906)
CAS号	867160-71-2
分子式	C26H23N5O
分子量	421.49
外观	White to yellow powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Linsitinib (formerly OSI-906; OSI 906) is a firs-in-class, ATP-competitive and orally bioavailable dual inhibitor of and insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF-1R) with potential antitumor activity. It exhibits modest potency against InsR with an IC50 of 75 nM, and it has no activity against other kinases like Abl, ALK, BTK, EGFR, FGFR1/2, PKA, and so on. In cell-free assays, it inhibits IGF-1R with an IC50 of 35 nM.