PD184352(Synonyms: CI-1040);CAS: 212631-79-3

规格	库存	目录价	会员专享价	数量
5 mg	3-5days	￥400.00	登录后可见	- +
10 mg	3-5days	￥650.00	登录后可见	- +
25 mg	3-5days	￥1160.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

5 mg

3-5days

￥400.00

登录后可见

- +

10 mg

3-5days

￥650.00

登录后可见

- +

25 mg

3-5days

￥1160.00

登录后可见

- +

基本信息

英文名称	PD184352(Synonyms: CI-1040)
中文名称	2-[(2-氯-4-碘苯基)氨基]-N-(环丙基甲氧基)-3,4-二氟-苯甲酰胺
CAS号	212631-79-3
分子式	C17H14ClF2 IN2O2
分子量	478.66
MDL	MFCD02683961
外观	White to off-white powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

PD184352 (PD-184352; CI-1040), an analog of benzhydroxamate, is an orally bioactive, specific, allosteric/non-ATP competitive MEK1/2 inhibitor with potential anticancer activity. In cell-based assays, it inhibits MEK1/2 with IC50 values of 17 nM and exhibits a 100-fold preference for MEK1/2 over MEK5. In mouse xenograft models, it exhibits strong in vitro anti-proliferative activity and significant in vivo antitumor efficacy.

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2-[(2-氯-4-碘苯基)氨基]-N-(环丙基甲氧基)-3,4-二氟-苯甲酰胺

212631-79-3 98+% 3-5days

￥400.00 5 mg