Cefalotin is a potent cephem antibiotic agent which inhibits class C β-lactamase AmpC, with an Ki of 0.32 µM. Cefalothin (Cefalotin) is a potent β-lactam cephalosporin antibiotic agent with a wide range antibacterial activity against gram-positive and gram-negative bacteria. It inhibits the growth of various Gram-positive and Gram-negative bacteria, including several strains of S. pyogenes, S. aureus, C. tetani, N. gonorrhoeae, Salmonella, and Shigella.
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