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醋酸卡泊芬净; 二醋酸卡泊芬净

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Caspofungin diacetate (Synonyms: MK-0991 diacetate; L-743872 diacetate;Caspofungin Acetate)

产品编号:CL2543 CAS No.:179463-17-3 MDLNo: 分子式:C56H96N10O19 分子量:1,213.42
规格 库存 目录价 会员专享价 数量
5 mg 3-5days ¥500.00 登录后可见
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10 mg 3-5days ¥800.00 登录后可见
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25 mg 3-5days ¥1500.00 登录后可见
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基本信息
英文名称 Caspofungin diacetate (Synonyms: MK-0991 diacetate; L-743872 diacetate;Caspofungin Acetate)
中文名称醋酸卡泊芬净; 二醋酸卡泊芬净
CAS号179463-17-3
分子式C56H96N10O19
分子量1,213.42
外观White to off-white powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
产品详情

Caspofungin acetate (formerly known as MK-0991), a cyclic lipopeptide, is a new class of antifungal drug. It is a semi-synthetic analogue of pneumocandin B0 with improved water solubility, a significant limitation in the development of the echinocandin class as pharmaceuticals. Caspofungin acts by inhibiting the synthesis of β (1,3)-D-glucan, an essential component of the cell wall of susceptible fungi. Incubation ofA. fumigatuwith a single dose of caspofungin affected the same proportion of apical and subapical branching cells for up to 72 h.The cells at the active centers for new cell wall synthesis withinA. fumigateshyphae are killed when they are exposed to caspofungin.

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