首页 > 产品目录 > 信号通路 > Metabolism(代谢) > Cathepsin (组织蛋白酶) > 奥当卡替

奥当卡替

ChemLeader 98+%

Odanacatib (Synonyms: MK-0822)

产品编号：CL2555 CAS No.：603139-19-1 MDLNo： 分子式：C25H27F4N3O3S 分子量：525.56

加入收藏分享给朋友

规格	库存	目录价	会员专享价	数量
1 mg	3-5days	￥1900.00	登录后可见	- +
5 mg	3-5days	￥4180.00	登录后可见	- +

化学品安全说明书(MSDS)

下载MSDS

发送询价加入购物车

基本信息
相关文档
产品详情
相关文献

基本信息

英文名称	Odanacatib (Synonyms: MK-0822)
中文名称	奥当卡替
CAS号	603139-19-1
分子式	C25H27F4N3O3S
分子量	525.56
外观	White to brown powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Odanacatib (also known as MK-0822) is a potent, neutral, and selective inhibitor of human/rabbit cathepsin K that may be applied to the management of bone metastases and osteoporosis. With IC50s of 0.2 nM/1 nM, it inhibits cathepsin K (human/rabbit) and shows good selectivity against off-target cathepsins B, L, and S. Odanacatib binds to cathepsin K specifically and inhibits its activity. This may reduce bone resorption, improve bone mineral density, and reverse osteoporotic changes. Approximately 16,000 postmenopausal osteoporosis patients are participating in a phase III trial to assess the potential of odanacatib to reduce fracture risk.
Keywords: buy Odanacatib | Odanacatib supplier | purchase Odanacatib | Odanacatib cost | Odanacatib manufacturer | order Odanacatib | Odanacatib distributor