英文名称 | Clofarabine |Clofarex | Evoltra | Clolar |
---|---|
中文名称 | 氯法拉滨 | 克罗拉滨 |
CAS号 | 123318-82-1 |
分子式 | C10H11ClFN5O3 |
分子量 | 303.68 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名称 | Clofarabine |Clofarex | Evoltra | Clolar |
---|---|
中文名称 | 氯法拉滨 | 克罗拉滨 |
CAS号 | 123318-82-1 |
分子式 | C10H11ClFN5O3 |
分子量 | 303.68 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Clofarabine, a nucleoside analogue for research of cancer, is a potent inhibitor of ribonucleotide reductase (IC50=65 nM) by binding to the allosteric site on the regulatory subunit.
Discovery and development of clofarabine: a nucleoside analogue for treating cancer.
PMID: 17016426 DOI: 10.1038/nrd2055
PMID: 27316580 DOI: 10.1016/j.kjms.2016.04.001